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Monthly Archives: June 2012

Development of an in vitro system for measuring fictive breathing in the neonatal brainstem/spinal cord

Faculty Mentor: Jeffrey Erickson Student: Robert Myers Pet-1 gene deletion results in a significant loss of neurons that comprise the brainstem serotonin (5HT) system. This selective loss of 5HT neurons results in abnormal autonomic function, particularly during early postnatal development. Pet-1 mutant (knockout) mice exhibit a lower resting breathing rate, a higher incidence of apneas,… Continue Reading

Effects of urbanization and extreme weather on the life cycle of a common songbird, The Carolina Chickadee

Faculty Mentor: Luke Butler Students: Sydney Hope & Frank Stabile Urbanization has important effects on the biology of a wide variety of organisms. Likewise, global climate change has altered the timing of important steps in the life cycles of many organisms. In birds, the annual replacement of the plumage is a critical life stage and… Continue Reading

Expanded Investigations into Remediation of Metal-Contaminated Water Through Electrospun Biopolymer Nanofibers

Faculty Mentor: Matthew Cathell Student: Melissa Bradley This project began during MUSE 2011 and is an expansion of ongoing research dealing with remediation of polluted water. The goal of our research is to create biopolymer fiber mats that successfully filter toxic metals out of water. These mats were made from the biopolymer alginate, a water-soluble polymer… Continue Reading

Development of a Damage Model for Fiber Reinforced Composite Materials

Faculty Mentor: Karen Yan Students: Daniel Christiansen A fiber reinforced composite (FRC) consists of two parts: high strength fibers and the resin that hold layers of these fibers together.  The directional specific strength and relative lightweight nature of these materials are perfect for advanced applications such as aerospace and automotive engineering.  While in most practical… Continue Reading

Modeling of friction-induced squeak of Ceramic-on-Ceramic Hip Implants

Faculty Mentor: Manish Paliwal Student: Mark Sidebottom Ceramic-on-Ceramic (CoC) bearings are an ideal choice for a total hip replacement because the ceramic bearings long wear life than Metal-on-Metal or Metal-on-Polyethylene bearings.  Recently CoC hips have been reported to squeak in 1-10% of the patients.  A study by Chevilotte et al. showed that in vitro testing… Continue Reading

A computational stochastic model of breathing embedded with fractal-like scaling

Faculty Mentor: Brett BuSha Student: George Banis While conscious, there is a stochastic feature of cardiorespiratory control that is responsible for natural variability, which can be expressed as a distribution of breath-to-breath (BBI) or heartbeat-to-heartbeat intervals (RRI). The integrative nature of the brain imparts memory into this system, where any present BBI or RRI is… Continue Reading

Fabrication of polymer and cellular composite constructs for tissue engineering applications

Faculty Mentor: Christopher Anderson Students: James Ferrie & Pamela Hitscherich Tissue engineering is a promising aspect of regenerative medicine that is aimed at constructing functional tissues and organs. This requires the integration of living cells, biodegradable materials, and biologically active molecules to promote cell and tissue growth.  Currently, challenges remain for more complex tissues/organs that… Continue Reading

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